分子生物学的发展历史.pptxVIP

第一章 分子生物学的发展历史;;The term has more than one definition.;遗传学（genetics）;1.2. 分子生物学发展简史;Transmission Genetics;In 1865, Gregor Mendel published Mendelian inheritance (孟德尔遗传定律 ).;;Molecular Genetics;The discovery of DNA;The Composition of Genes;How does genes work?;The overall structure of DNA;Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid (Nature, April 25, 1953. volume 171:737-738.) ;Rosalind Frankin;James Watson (34y) Francis Crick (46y) Maurice Wilkins (46y);1958，Matthew Meselson and Franklin Stahl proved that DNA replication in bacteria follows the semiconservative pathway.;;Francois Jacob and Sydney Brenner;In the early 1960s Marshall Nirenberg Gobind Khorana Robert W. Holley ;one gene; Howard Temin (41y);The Nobel Prize in Chemistry 1980;for his work on the structure of proteins, especially that of insulin;1983. Barbara McClintock (86y);The Nobel Prize in Chemistry 1989;;;In 1997, lan Wilmut and colleagues cloned a sheep (Dolly) from an adult sheep udder cell.;1997，The Nobel Prize in Physiology or Medicine ;discovered key regulators of the cell cycle;2002 Nobel Prize John Sulston Sydney Brenner H. Robert Horvitz;1.3. 分子生物学的研究概况;还原论;人类对生命现象的认识;人类对生命现象的认识;;分子生物学;21世纪生命科学发展的特点;Francois Jacob and Sydney Brenner;;;还原论;还原论;21世纪生命科学发展的特点