系统性血管炎.ppt

仿疮合施己壶酱守咳俯疾暴踪悯廓窑忱坚眯彭育恩浪统筑肛叭小迹奋拌食系统性血管炎2013系统性血管炎2013 Reference Number of patients Glucocorticoids before (mg/day) Glucocorticoids during (mg/day) Improvement on vascular imaging, modality Relapse after discontinuation, interval Salvarani 1 12.5 2.5 Yes, PET/CT 1 of 1,5 months Seitz et al. 3 19 – Yes, MRA,n = 1 – Sciascia 2 25 – – – Beyer et al. 3 30 ***7.5 Yes, PET/CT,n = 2 – Vinit et al. 1 20 – of 1,6 months Unizony et al. 7 25.5 2.2 – of 1,2 months Besada and Nossent 1 20 10 Yes, MRI and US of 1,2 months Christidis et al. 1 20 3.5 Yes, PET/CT – IL-6单抗：难治性GCA 赖妖狱呆优房矮艘踊杖庸斑慕舅减协键某辱件永塑瓜状捷湾迅集凡伦绒掐系统性血管炎2013系统性血管炎2013 Reference n GCs before (mg/day) GCs during (mg/day) Improvement on vascular imaging Relapse after discontinuation Nishimoto 1 30 7.5 Yes, CT – Salvarani 2 0–12.5 0 Yes, PET/CT, n = 2 0 of 2 Seitz 2 37.5 6 Yes, MRA, n = 2 during treatment Unizony 2 11 0.9 Yes, PET/CT, n = 1 – Bredemei 1 30 5 No, CT of 1, 3 months Salvarani 1 12.5 0 Yes, PET/CT of 1, 2 months IL-6单抗：难治性TA 千挨任原左庞婆粒籍脆定鸡柿叭讳慷镶舶名闰挖王剃请蜕禾启研晰扛眯压系统性血管炎2013系统性血管炎2013 Disease activity (BVAS) 8/10 achieved remission on 7.5mg pred/d. No relapses on Mepolizumab Stopped Mep, 7/8 relapses w/in 10 months 抗IL-5 (Mepolizumab) 治疗EGPA（CSS）： Kim S et al. J Allergy Clin Immunol 2010;125:1336-43 沤悟胶帕欧赵计襟未蜀柳缩以烙锹慷挝厩颁峦喻跃占仿刃没妖汹沈半英伪系统性血管炎2013系统性血管炎2013 嗜酸细胞计数： Eosinophils 义巷兵窑未盅懊终茎炸要狸淑袭踢求剁麓牧歼伤袍凹群允溜翅艰件都躲缉系统性血管炎2013系统性血管炎2013 Thanks 醛竟早保坦燎顷蚊笛购硅贤菱友叮涅凳镑章警科错乎吩闺递娄茵减械矣意系统性血管炎2013系统性血管炎2013 Note：FDG:氟代脱氧葡萄糖 Prev Abstract#: 2362 Next Abstract Submissions ACR Evaluation of Disease Activity Using FDG PET-CT in Patients with Large Vessel Vasculitis Presenter: Giulia Pazzola: Arcispedale S Maria Nuova, IRCCS Date: Tuesday, November 13 Time: 9:00 AM - 6:00 PM  Location: Poster Hall (Hall B) Session Title: Vasculitis Category: Vasculitis vasculitis, diagnostic imaging Keywords: vasculitis, diagnostic imaging Save to My Itinerary Submit Evaluation Unavailable Background/Purpose: 18F-Fluorodeoxyglucose (FDG