难治性丙肝的治疗现状及发展趋势（63页）.pptVIP

2021/4/26 * * SVR, sustained virologic response. ? One question with regard to SVR is whether the most important predictive feature is duration of therapy or viral kinetics showing a prompt response early in therapy. Genotype 1/4 patients who have experienced a rapid virologic response by Week 4 and then extend their therapy for another 44?weeks have a very high SVR rate. However, patients who do not become HCV RNA negative until 12 weeks or 24?weeks and are treated for a total of 48 weeks have progressively lower SVR rates. However, if patients’ treatment is extended to a total of 72?weeks of