SLE-目标治疗-协和医院-赵岩.pptxVIP

狼疮：“目标(mùbiāo)治疗” 的曙光？2012 第一页，共64页。CD20(Rituximab): RCT研究(yánjiū) EXPLORER LUNAR BELIEVERS RINGAssessment of flares in lupus patients enrolled in a phase II/III study of rituximab (EXPLORER).Lupus. 2011 Jun;20(7):709-16. Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study. Arthritis Rheum. 2012 ; 64(4):1215-26.第二页，共64页。EXPLORER研究：首个狼疮治疗研究的RCT目标(mùbiāo)治疗，并以失败告终评价体系：BILAGAssessment of flares in lupus patients enrolled in a phase II/III study of rituximab (EXPLORER). Lupus. 2011; 20(7):709-16. 第三页，共64页。C