第六章 有机酸.pptVIP

学习文档 2. Metabolic regulation of citric acid production by A. niger （1） Phosphofructokinase (PFK) inhibited by a high internal concentration of ATP （2） α- keto-glutarate dehydrogenase inhibited by glucose and ammonium (NH4+) 学习文档 Three excess and three limiting Excessive concentrations Glucose Ammonium (NH4+) Dissolved oxygen -An alternative respiratory pathway without the formation of ATP -Sudden interruptions in aeration cause an irreversible impairment of citric acid production 学习文档 Phosphate limitation Mn2+ deficiency Results