肺癌骨转移治疗资料PPT课件.ppt

* ＋ * In the placebo-controlled trials of pamidronate and zoledronic acid, the placebo arm provides an accurate picture of the extent to which patients suffer these various skeletal complications Radiation to bone and pathologic fractures are the most common events, reflecting the burden of bone pain and the fragility of patients’ bones Patients with breast cancer have the highest incidence of skeletal complications—approximately half the patients in the placebo arm experienced a fracture over the 2 years on study, and 11% of patients required orthopedic surgery Therefore, there is a great ne