糖尿病肾病患者血液白细胞的变化.doc

糖尿病肾病患者血液白细胞的变化 目录 TOC \o "1-9" \h \z \u 目录 1 正文 1 文1：糖尿病肾病患者血液白细胞的变化 1 1 对象和方法 2 2 结果 3 3 讨论 4 文2：糖尿病肾病患者血液透析的护理体会 5 1 资料与方法 5 2 结果 8 参考文摘引言： 8 原创性声明（模板） 9 文章致谢（模板） 10 正文 糖尿病肾病患者血液白细胞的变化 文1：糖尿病肾病患者血液白细胞的变化 Varieties of Blood Leucocytes in Patients with Diabetic Nephropathy Abstract： Objective To study the varieties of blood leucocytes in the patients with diabetic nephropathy and to analyze the influence of inflammation on diabetic All the 436 inpatients with diabetes were divided into diabetic group with nephropathy (n=102) and diabetic group without nephropathy (n=334). The totalities of blood leucocytes and neutrophils were count. Results The leukocytic totalities of the two groups were respectively (±)×109/L and (±)×109/L, and the difference between them was significant (t=,P<). The neutrophilic totality of the former group [(±)×109/L] was obviously higher than that of the latter group [(±)×109/L], and the difference between them was notably significant (t=,P<). As for correlation analysis, the totality of leucocytes was positively correlative with creatinine and urea, and was of no obvious correlation with blood glucose. The totality of neutrophils was obvious positive correlative with creatinine, urea and blood glucose. Conclusion The totality of leucocyte in diabetic blood rises. It is positively correlative with the levels of creatinine and urea. There is an inflammatory reaction in diabetes mellitus, which has an influence on the occurrence and the progress of diabetic nephropathy. Key words： diabetes mellitus; white blood cell count; renal damage 糖尿病肾病是糖尿病的主要并发症，其发生发展涉及许多因素。近年来，在糖尿病、胰岛素抵抗及大血管病变研究中，炎症学说成为热点之一。但炎症与糖尿病微血管病变的研究报道较少。我们对糖尿病肾病患者的白细胞计数、中性粒细胞计数进行检测分析，旨在了解炎症反应与糖尿病肾病的关系。 1 对象和方法 对象 选择我院内分泌科2002年3月—2005年11月住院糖尿病病人作为观测对象，均符合1999年WHO糖尿病诊断标准[1]。共436例，其中男性255例，女性181例，年龄为19~91岁，平均年龄岁。根据肾功能改变分为两组：(1)糖尿病肾病组：102例，男61例，女41例，年龄26~81岁，平均年龄岁，血清肌酐（Cr）和(或)血清尿素（Urea）升高；(2)糖尿病无肾病组：334例，男194例，女140例，年龄19~91岁，平均年龄岁，肾功能检查正常。两组均排除其他肾脏疾