2型糖尿病合并肥胖血糖和体重管理规范PPT幻灯片.ppt

* * * 不同基础胰岛素对体重的影响是不同的。 一般来说，胰岛素治疗往往在治疗的六个月和三年后引起的体重增加最多，可以达到4.8到7.8公斤，而大部分体重增加会出现在最初应用胰岛素的三个月。和NPH胰岛素和甘精胰岛素相比，地特胰岛素是目前唯一具有体重优势的基础胰岛素，短期应用不增加体重，1年后体重增加较甘精胰岛素少，且 体重优势随着BMI的增加而增加的特点。 * * Based on the presented evidence, the effect of insulin detemir on weight gain is unlikely to be explained by just one of the hypotheses discussed, but by a combination of them. It has been consistently demonstrated that insulin detemir reduces energy intake, and it appears that this shift in energy balance is not associated with a lower incidence of hypoglycaem