第12章碳负离子的反应.pptxVIP

第 12 章 碳负离子的反应 Reaction of Carbanion;一、 α -氢的酸性 (Acidity of α-hydrogen); ; ;;结构因素：吸电子基团;; ;98 %;Phenol is unusual in that its enol tautomer is more stable than its keto tautomer. Because the enol tautomer is aromatic, but the keto tautomer is not.;烯醇互变的化学或立体化学结果：; α –碳的构型转化导致消旋化 （Racemization） An optically active aldehyde or ketone with a stereocenter at the α-carbon can racemize in the presence of catalytic acid or base.;Condensation reaction: a reaction that combines two molecules while removing a small molecule (usually water or an alcohol). 缩合反应是增长碳链、改变分子骨架的重要手段。;（一） Perkin 反应;