Agilent Determination of Chloramphenicol in Fish Meat by Liquid Chromatograph-Atmospheric Pressure Photo Ionization-Mass Spectrometry (LC-APPI-MS) 说明书用户手册.PDF

Determination of Chloramphenicol in Fish Meat by Liquid Chromatograph-Atmospheric Pressure Photo Ionization-Mass Spectrometry (LC-APPI-MS) Application Foods, Environmental Author therapy can result in a well-understood and irre- versible type bone marrow depression called apla- Masahiko Takino and Shigeki Daishima sia or hypolasia. This, in turn, can lead to aplastic Yokogawa Analytical Systems Inc anemia and although uncommon, it is often fatal. 2-11-13, Nakacho, Musashino Because of these health concerns, a joint Food and Tokyo, 180-8453 Agriculture Organization/World Health Organiza- Japan tion (FAO/WHO) Expert Committee on Food Addi- tives has proclaimed that CAP residues in the human food supply are unacceptable [1]. The use Abstract of CAP in food products has been banned in EU and U.S.A. However, CAP’s broad-spectrum activ- A liquid chromatography-atmospheric pressure ity, ready availability, and low cost attract its use photoionization-mass spectrometry method was devel- by some third world countries. Admittedly, when- oped for the determination of chloramphenicol antibiotics ever CAP is accessible, indiscriminate and illegal in fish m