子宫内膜癌 课件.pptVIP

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  • 2022-08-24 发布于浙江
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特殊组织类型癌的手术方式 (子宫内膜浆乳癌、透明细胞癌) 恶性程度高 ,早期即有淋巴转移及盆腹腔转移, 即使癌变局限于子宫内膜,30%~50%已有子宫外病变,且多向上腹转移。 临床Ⅰ期,复发率31%-50%; 5年存活率: Ⅰ期40%-50%,晚期15% 其手术应与卵巢癌相同,除进行分期探查、切除子宫 +双侧附件 +腹膜后淋巴结外 , 切除大网膜及阑尾。 术后化疗(TP、CP 、CAP方案) * . 病理组织类型 国际妇科病理协会(ISGP)1987 (高危型子宫内膜癌) 浆液性癌 Serous carcinoma 粘液性癌 Mucinous carcinoma 透明细胞癌 Clear cell carcinoma 鳞状细胞癌 Squamous cell carcinoma 混合型癌 Mixed carcinoma 未分化癌 Undifferentiated carcinoma 混杂癌 Miscellanous carcinoma 转移癌 Metastasis * . 病理特点 大体表现(1) 可发生在子宫各部位,宫体部位较多 不同组织类型的癌肉眼无明显区别 侵肌时子宫体积增大, 浸润肌层癌组织境界清楚, 呈坚实灰白色结节状肿块。 * . 局限型 弥漫型 * . This adenocarcinoma of the endometrium is more obvious. Irregular masses of white tumor are seen over the surface of this uterus that has been opened anteriorly. The cervix is at the bottom of the picture. This enlarged uterus was no doubt palpable on physical examination. Such a neoplasm often present with abnormal bleeding. The endometrial adenocarcinoma is present on the lumenal surface of this cross section of uterus. Note that the neoplasm is superficially invasive. The cervix is at the right. 子宫内膜癌 III 期 侵肌全层、宫颈、附件 侵肌 * . 子宫内膜癌侵肌 子宫内膜癌 子宫内膜增生 (息肉样) * . 子宫内膜腺癌G1 子宫内膜腺癌G2 子宫内膜腺癌G3 * . 子宫内膜浆乳癌 子宫内膜腺棘癌 Serous carcinoma Adenocanthoma adenocarcinoma * . 子宫内膜腺鳞癌 Adenosquamous adenocarcinoma 子宫内膜鳞状细胞癌 Squamous cell carcinoma * . 子宫内膜透明细胞癌 子宫内膜粘液腺癌 Clear cell carcinoma Mucinous carcinoma * . 子宫内膜癌分期的意义 子宫内膜癌临床分期 (FIGO,1971) (Clinical staging) 用于单纯放疗/术前 15%-20%不能准确符合真实分期。 子宫内膜癌手术病理分期(FIGO,1988) ( Surgical pathological staging ) 组织学分级、肌层侵犯、子宫外转移、淋巴转移 * . 子宫内膜癌临床分期 (FIGO,1971)(Clinical staging) 用于单纯放疗/术前 Ⅰ期 癌局限于宫体 Ⅰa 子宫腔长度≤8cm Ⅰb 子宫腔长度>8cm 腺癌组织学分级:G1 高分化腺癌 G2 中分化腺癌 G3 低分化腺癌 Ⅱ期 癌瘤

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