Agilent Quantitation of a Dinitro Flavonoid (DNF) in Plasma Using the 1200L LC MS MS System Application Note说明书用户手册.PDF

Application LC/MS Note Number 14 February 2004 Quantitation of a Dinitro Flavonoid (DNF) in Rat Plasma Using the Varian 1200L LC/MS/MS System D. Garteiz, R. Morrow, and B. Alexander, TexMS Analytical Services, Houston, TX C. Schmidt, Varian, Inc., Walnut Creek, CA Introduction HPLC Conditions Flavonoids are compounds that make up the pigments in Column 5.0 cm by 2.0 mm, 5 µm C-18 fruits, vegetables, and herbs. There have been reports of Solvent A acetonitrile:water (50:50) flavonoids having multiple beneficial therapeutic effects for a Solvent B acetonitrile:water (95:5) in 0.1% formic acid large number of serious illnesses, such as rheumatoid arthritis, cancer, cataracts, anxiety, and depression. The objective of LC Program Time %A %B Flow (min) (µL/min) this work was to carry out a pharmacokinetic evaluation to 0:00 99 1 200 determine a profile with the formulation being tested at increasing doses where there is pharmacological effect. 3:50 1 99 200