BMf-BH3-DataSheet-生命科学试剂-MedChemExpress.pdf免费

Hotline: 400-820-3792 Inhibitors • Agonists • Screening Libraries www.MedChemE BMf-BH3 Cat. No.: HY-P1733 分⼦式: C₁₃₁H₂₁₄N₄₅O₃₅S 分⼦量: 3012.5 Sequence: {Leu}{Gln}{His}{Arg}{Ala}{Glu}{Val}{Gln}{Ile}{Ala}{Arg}{Lys}{Leu }{Gln}{Cys}{Ile}{Ala}{Asp}{Gln}{Phe}{His}{Arg}{Leu}{His}{Thr} Sequence Shortening: LQHRAEVQIARKLQCIADQFHRLHT 作⽤靶点: Others 作⽤通路: Others 储存⽅式: Please store the product under the recommended conditions in the COA. BIOLOGICAL ACTIVITY ⽣物活性 BMf-BH3 属于 Bcl-2 凋亡介质家族。BH3-only protein，Bmf 是组蛋⽩脱⼄酰基酶 (HDAC) 抑制剂介导的增强 电离辐射诱导细胞死亡的关键因⼦ [1] [2]。 REFERENCES [1]. Zhang Y, et al. Bmf contributes to histone deacetylase inhibitor-mediated enhancing effects on apoptosis after ionizing radiation. Apoptosis. 2006 Aug;11(8):1349-57. [2]. Puthalakath H, et al. Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science. 2001 Sep 7;293(5536):1829-32. McePdfHeight Caution: Product has not been fully validated for medical applications. For research use only. Tel: 400-820-3792; 021