CDK-HDAC-IN-1-DataSheet-生命科学试剂-MedChemExpress.pdf

Hotline: 400-820-3792 Inhibitors • Screening Libraries • Proteins www.MedChemE CDK/HDAC-IN-1 Cat. No.: HY-132914 分⼦式: C₂₀H₁₈N₄O₄ 分⼦量: 378.38 作⽤靶点: CDK 作⽤通路: Cell Cycle/DNA Damage 储存⽅式: Please store the product under the recommended conditions in the Certificate of Analysis. BIOLOGICAL ACTIVITY ⽣物活性 CDK/HDAC-IN-1 显⽰出显著的 CDK2/4/6 和 HDAC6 抑制活性（IC50 = 60.9 ± 2.9, 276 ± 22.3, 27.2 ± 4.2, 和 128.6 ± 0.4 nM）。 REFERENCES [1]. Cao Z, et al. Indirubin Derivatives as Dual Inhibitors Targeting Cyclin-Dependent Kinase and Histone Deacetylase for Treating Cancer. J Med Chem. 2021 Oct 28;64(20):15280-15296. McePdfHeight Caution: Product has not been fully validated for medical applications. For research use only. Tel: 400-820-3792; 021 Fax: 021 E-mail: tech@MedChemE 1/1 Master of Bioactive Molecules — 您⾝边的抑制剂⼤师