陕西师范大学分子生物学课件-Chapter4.pptVIP

Chapter 4Gene Translation: RNA → Protein陕西师范大学《分子生物学》 4.1 Translation System 1. Genetic codon? Degeneracy? Generality? Particularity? Codon Anticodon Wobble hypothesis 2. mRNA structure mRNA structure of prokaryotes polycistron Shine-Dalgarno sequence mRNA structure of eukaryotes single cistron 5’-cap 3’-poly(A) 3. tRNAExtra armAcceptor armAnticodon loopD loopTψCG loopcloverleaf structure tertiary structure Upside-down “L”(倒L形) size of ribosomeSize of subunitsRatio(RNA : protein)prokaryotes70S50S, 30S2 : 1mammalian80S60S, 40S 3 : 25. Riboso