Catechin-7-O-β-D-glucopyranoside-DataSheet-生命科学试剂-MCE.pdf

Hotline: 400-820-3792 Inhibitors • Screening Libraries • Proteins www.MedChemE Catechin 7-O-β-D-glucopyranoside Cat. No.: HY-N10587 CAS No.: 65597-47-9 分⼦式: C₂₁H₂₄O₁₁ 分⼦量: 452.41 作⽤靶点: Others 作⽤通路: Others 储存⽅式: Please store the product under the recommended conditions in the Certificate of Analysis. BIOLOGICAL ACTIVITY ⽣物活性 Catechin 7-O-beta-D-glucopyranoside 是⼀种具有⼝服活性天然产物，发现于 Ulmus davidiana 和 Paeonia obovata。Catechin 7-O-beta-D-glucopyranoside 具有抗氧化和抗炎活性，并可减轻线粒体功能障碍，可⽤于 肠道炎症性疾病的研究。 体外研究 Catechin 7-O-β-D-glucopyranoside (10 μg/mL; 24 h) shows protective effect against Streptozotocin-induced cell damage by its antioxidant effects and the attenuation of mitochondrial dysfunction [3]. Western Blot Analysis [3] Cell Line: RINm5F rat pancreatic β-cells Concentration: 10 μg/mL Incubation Time: 24 hours Result: Increased the MnSOD level attenuated by Streptozotocin treatment. Restored the Streptozotocin-induced reduction in mitochondrial CAT level. 体内研究 Catechin 7-O-β-D-glucopyranoside (intraperitoneal injection; 10 mg/kg; once) treatment shows mild protective effect against lethality induced by LPS/D-GalN [1]. Catechin 7-O-β-D-gluc