2-3-cGMP-sodium-Guanosine-2-3-cyclic-monophosphate-sodium-salt-DataSheet-生命科学试剂-MCE.pdf

Hotline: 400-820-3792 Inhibitors • Screening Libraries • Proteins www.MedChemE 2,3-cGMP sodium Cat. No.: HY-N8245 CAS No.: 15718-49-7 Synonyms: Guanosine 2,3-cyclic monophosphate sodium salt 分⼦式: C₁₀H₁₁N₅NaO₇P 分⼦量: 367.19 作⽤靶点: Others 作⽤通路: Others 储存⽅式: Please store the product under the recommended conditions in the Certificate of Analysis. BIOLOGICAL ACTIVITY ⽣物活性 2,3-cGMP sodium，⼀种 cGMP 类似物，是⼀种双酶催化裂解 RNA 过程中产⽣的中间体。 体外研究 2,3-cGMP sodium (10 nM-100 μM, 120 min) reduces the active transport of [3H]3’,5’-cGMP into inside-out vesicles from human erythrocytes [2]. 2,3-cGMP sodium (2 μM) increases the ATPase activity [2]. REFERENCES [1]. Sokurenko JV, et al. [Identification of 2,3-cGMP as an intermediate of RNA catalytic cleavage by binase and evaluation of its biological action]. Bioorg Khim. 2015 Jan-Feb;41(1):37-43. Russian. [2]. Boadu E, et al. Inhibition by guanosine cyclic monophosphate (cGMP) analogues of uptake of [(3)H]3,5-cGMP without stimulation of ATPase activity in human erythrocyte inside-out vesicles. Biochem Pharmacol. 2001 Aug 15;62(4):425-9. McePdfHeight