(58)--5.2.4补体三条激活途径的特点.pptVIP

医学免疫学（第7版） * * Figure 3-19 Mechanisms of action of some complement regulatory proteins (a) C1 inhibitor binds to activated C1r and C1s on C1q and causes their dissociation. (b) CR1 binds to and causes dissociation of either form of C3 convertase and recruits factor I, which cleaves and thereby inactivates C3b (or C4b, not shown). (c) DAF induces dissociation and thus inactivation of C3 convertase. (d) The soluble regulator factor H binds to C3b on sialic acid-containing cell surfaces (for example, host cells), and targets factor I to cleave C3b. The transmembrane protein MCP similarly promot