脂肪酸在急重症的应用.pptxVIP

脂肪酸在急重症的应用第1页/共51页 Lipid Mediator Synthesis第2页/共51页 Impact of n-3 vs. n-6 Fatty Acids on Inflammation第3页/共51页 Key Features of Acute Lung Injury pulmonary hypertension VQ-mismatch / Shuntvasomotor dysfunction vascular leakagegas exchange ?secundary bacterial invasionQO2O2O2 leukocyte invasionCapillary sequestrationAlveolar invasionN-3 Lipids第4页/共51页 Randomized, controlled study21 Pts with septic ARDS LCT or LCT/MCT @ 12g/hPulmonary hemodynamics / Ventilation parameter第5页/共51页 ResultsLCT (n-6)Increase in Pulmonary Artery Pressure (MPAP) Decrease in Oxygenation-Index (PaO2 / FiO2)第6页/共51页