复方甘草酸苷联合地氯雷他定治疗慢性荨麻疹的效果分析.docxVIP

? ? 复方甘草酸苷联合地氯雷他定治疗慢性荨麻疹的效果分析 ? ? Summary：目的：探讨复方甘草酸苷联合地氯雷他定治疗慢性荨麻疹的效果。方法：研究起始-截止时间分别为2021年1月-2022年6月，共有观察对象（慢性荨麻疹患者）70例入组，以随机数字表法将患者分组（共两组，每组患者35例），一组为观察组应用复方甘草酸苷联合地氯雷他定治疗，一组为对照组应用单独地氯雷他定治疗，对比不同治疗方案的临床应用效果。结果：观察组中患者临床治疗总有效率97.15%（34/35）高于对照组82.85%（29/35），（p＜0.05）。观察组中患者红肿症状消失时间（3.49±0.85）d低于对照组（5.89±1.06）d；瘙痒症状消失时间（3.88±0.63）d也低于对照组（5.41±0.92）d，（p＜0.05）。结论：复方甘草酸苷联合地氯雷他定治疗慢性荨麻疹的效果显著，可参考应用。 Keys：复方甘草酸苷；地氯雷他定；慢性荨麻疹；效果分析 Abstract: Objective: To investigate the effect of compound glycyrrhizin combined with desloratadine in the treatment of chronic urticaria. Methods: The starting and ending time of the study were from January 2021 to June 2022. A total of 70 patients (chronic urticaria patients) were enrolled in the study. The patients were pided into two groups by random number table (35 patients in each group). One group was treated with compound glycyrrhizin combined with desloratadine, the other group was treated with desloratadine alone, and the clinical effects of different treatment schemes were compared. Results: the total effective rate of the observation group was 97.15% (34/35), higher than that of the control group 82.85% (29/35) (p0.05). The disappearance time of redness and swelling in the observation group (3.49 ± 0.85) days was lower than that in the control group (5.89 ± 1.06) days; The disappearance time of pruritus symptom (3.88 ± 0.63) d was also lower than that of the control group (5.41 ± 0.92) d (p0.05). Conclusion: Compound glycyrrhizin combined with desloratadine is effective in the treatment of chronic urticaria. Key words: compound glycyrrhizin; Desloratadine; Chronic urticaria; Effect analysis 慢性荨麻疹是临床中常见的皮肤性疾病，主要表现为皮肤、黏膜、血管的炎性充血与组织水肿。慢性荨麻疹的病程时间较长，且病情易反复发作，并引起皮疹、食欲不振、发热、头痛、全身不适等症状，严重影响患者的身心健康。目前临床中针对慢性荨麻疹主要以药物干预治疗，但在药物选择上临床仍存在不同的讨论[1]。本次研究即由此展开，围绕复方甘草酸苷联合地氯雷他定治疗的临床应用优势，以对比模型的形式，入组案例对象（慢性荨麻疹患者）70例，过程报道如下。 1资料与方法 1.1一般资料 研究起始-截止时间分别为2021年1月-2022年6月，共有观察对象（慢性荨麻疹患者）70例入组，以随机数字表法将患者分组（共两组，每组患者35例），一组为观察组应用复方甘草酸苷联合地氯雷他定治疗，一组为对照组应用单独地氯雷他定治疗。观察组中