HHS Public Access
Author manuscript
A Lancet Gastroenterol Hepatol . Author manuscript; available in PMC 2017 December 04.
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Published in final edited form as:
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r Lancet Gastroenterol Hepatol . 2017 April ; 2(4): 269–276. doi:10.1016/S2468-1253(17)30004-3.
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Risk of colorectal cancer in Asian patients with ulcerative colitis:
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t a systematic review and meta-analysis
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Sawan Bopanna, M.D , Ashwin N Ananthakrishnan, M.D , Saurabh Kedia, M.D , Vijay
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Yajnik, M.D, Ph.D. , and Prof. Vineet Ahuja, M.D
1Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India
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A Massachusetts General Hospital, Crohn’s and Colitis Center, 165 Cambridge St., Boston, MA,
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t U.S.A
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M Summary
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u Background—The increased risk of colorectal cancer in ulcerative colitis is well known. The
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c risk of sporadic colorectal cancer in Asian populations is considered low and risk estimates of
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p colorectal cancer related to ulcerative colitis from Asia vary. This meta-analysis is an Asian
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perspective on the risk of colorectal cancer related to ulcerative colitis.
Methods—We searched PubMed and Embase for terms related to colorectal cancer in ulcerative
colitis from inception to July 1, 2016. The search for published articles was done by country for all
countries in Asia. We included studies with information on the prevalence and cumulative
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