临床合理用药中细菌耐药与临床微生物检验的应用研究.docx

汝州市金庚康复医院 RUZHOU JINGENG REHABILITION HOSPITAL ———————————————————————————————————————————— PAGE PAGE 1 临床合理用药中细菌耐药与临床微生物检验的应用研究 【摘要】目的：探讨临床合理用药中细菌耐药与临床微生物检验的应用研究。方法：选取2020年1月-2021年12月期间62例患者送检标本为研究资料。取62例患者的血压标本、尿液标本、痰液标本、分泌物标本等进行微生物检验，使用全自动细菌分析仪及配套鉴定卡开展药敏试验及菌株鉴定，观察病原菌分布及其耐药性。结果：此次纳入62例患者中共培养出致病菌53株。病原菌耐药性分析结果不同，如文中表2所示。结论：微生物以及细菌耐药性检验可对临床合理用药提供依据，并起到指导作用，值得推广。 【关键词】临床合理用药;细菌耐药；临床微生物检验；应用研究 Application of bacterial drug resistance and clinical microbiological test in clinical rational drug use Zhang Ying (Heilongjiang Daqing Oilfield General Hospital, Heilongjiang Daqing 163001) [Abstract] Objective: To explore the application of bacterial drug resistance and clinical microbiological test in clinical rational drug use. Methods: samples from 62 patients from January 2020 to December 2021 were selected as the research data. The blood pressure samples, urine samples, sputum samples and secretion samples of 62 patients were taken for microbiological examination. The automatic bacterial analyzer and supporting identification card were used to carry out drug sensitivity test and strain identification, and the distribution and drug resistance of pathogenic bacteria were observed. Results: a total of 53 strains of pathogenic bacteria were cultured in 62 patients. The results of drug resistance analysis of pathogens are different, as shown in Table 2. Conclusion: microbial and bacterial drug resistance test can provide basis for clinical rational drug use and play a guiding role, which is worth popularizing. [Key words] clinical rational drug use; Bacterial resistance; Clinical microbiological examination; application research 多重耐药菌则指一种细菌对两种及以上药物产生耐药性的情况，多重耐药菌感染发生后可大大增加疾病控制难度及继发性感染风险，危及患者生命健康[1]。因而强化细菌耐药性及临床微生物检验尤为关键[2]。对此，此次研究主要以在本院接受微生物及细菌耐药性检验的62例患者为例，分析细菌耐药与临床微生物检验对临床合理用药的指导作用。报告如下。 1.资料与方法 1.1 一般资料 选取2020年1月-2021年12月期间62例患者送检标本为研究资料。纳入患者中男32例、女30例；年龄25-71（48.56±6.37）岁。研究中已排除同病例相同部位标本中连续分离的相同菌株。 1.2 方法 取62例患者的血压标本、尿液标本、痰液标本、分泌物标本等进行微生物检验，使用全自动细菌分析仪及配套鉴定卡开展药敏试验及菌