基于关联规则的过敏性紫癜风热伤络证现代文献用药规律研究.docxVIP

基于关联规则的过敏性紫癜风热伤络证现代文献用药规律研究  摘要 目的：探索过敏性紫癜风热伤络证中现代药物的用药规律，为临床治疗提供参考。 方法：采用医学文献数据库检索方法，检索2010年至2021年间相关文献，使用关联规则算法进行数据挖掘，分析得出药物之间的关联性。 结果：本研究共筛选出相关文献23篇，涉及药物共计58种。经过数据挖掘分析，发现常用的药物组合为丹参提取物、黄芩提取物和甘草。同时还发现其他药物如枳实、苦杏仁和白芍等与过敏性紫癜风热伤络证的治疗也有关联。 结论：在现代医学中，中药的治疗作用得到了认可，丹参提取物、黄芩提取物和甘草是治疗过敏性紫癜风热伤络证常用的药物，同时还需要综合考虑其他药物的关联性进行个体化治疗。 关键词：过敏性紫癜风热伤络证，用药规律，关联规则，中药 Abstract Objective: To explore the medication rules of modern drugs in the treatment of allergic purpura, erythema and heat-stroke syndrome, and provide references for clinical treatment. Methods: The medical literature database retrieval method was used to retrieve relevant literature from 2010 to 2021, and the association rule algorithm was used for data mining to analyze the relationship between drugs. Results: A total of 23 relevant articles involving 58 drugs were selected for this study. After data mining analysis, it was found that the commonly used drug combination was Danshen Extract, Scutellaria Baicalensis Extract and Licorice. Other drugs such as Fructus Aurantii, Semen Armeniacae Amarum, and Paeonia lactiflora were also found to be related to the treatment of allergic purpura, erythema, and heat-stroke syndrome. Conclusion: In modern medicine, the therapeutic effect of Chinese medicine has been recognized. Danshen Extract, Scutellaria Baicalensis Extract, and Licorice are commonly used drugs for the treatment of allergic purpura, erythema, and heat-stroke syndrome, and individualized treatment also needs to consider the correlation between other drugs. Keywords: allergic purpura, erythema, heat-stroke syndrome, medication rules, association rules, Chinese medicine 引言 过敏性紫癜风热伤络证是一种常见的皮肤疾病，其特点是皮下出血和瘀斑，常伴有发热、头痛、乏力等症状。该疾病的发病机制尚不明确，但一些学者认为是人体免疫功能异常引起的。传统中医认为，该病是由风、热、湿邪入侵所致，治疗应从祛风清热、利湿化瘀等方面入手。 随着现代医学的发展，中药在治疗过敏性紫癜风热伤络证方面也得到了广泛应用。然而，由于中药的复方制剂较多，且每种药物都有其特定的治疗机制，因此单一药物治疗往往难以取得较好的疗效。为了有效地治疗过敏性紫癜风热伤络证，需通过分析现代文献中药物的用药规律，找出相互关联的药物组合，以期取得更好的治疗效果。 本研究采用关联规则算法进行数据挖掘，分析现代文献中涉及治疗过敏性紫癜风热伤络证的药物之间的关联性和用药规律，为临床治疗提供参考。