内科学教学课件：癫痫Epilepsy.pptVIP

神经调控治疗 脑深部刺激 经颅磁刺激 迷走神经刺激 Dorsal Midbrain antiepileptic Zone, DMAZ Glutamatergic input from STN keep the SNr firing at a high rate. The GABAergic inhibitory output from SNr keeps a constant inhibition of the DMAZ. Animal and clinical studies have shown that high frequency stimulation of STN produces a functional inhibition of STN and result in disinhibition of DMAZ with a corresponding antiseizure effect. Transcranial Magnetic Stimulation, rTMS At the same intensity, the bigger amplitude and the lower threshold of MEP, the higher excitability of motor cortex. Vagal nerve stimulation, VNS