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基因预测的概念及意义 原核基因识别 真核基因预测的困难性 真核基因预测的依据 真核基因预测的基本步骤及策略 真核基因预测方法及其基本原理 2、基因预测 当前第94页\共有172页\编于星期五\4点 Human Fugu worm E.coli Why is Gene Prediction Challenging? Coding density: as the coding/non-coding length ratio decreases, exon prediction becomes more complex. Some facts about human genome Coding regions comprise less than 3% of the genome There is a gene of 2400000 bps, only 14000 bps are CDS ( 1%) 2.3 真核基因预测的困难性 当前第95页\共有172页\编于星期五\4点 worm E.coli Splicing of genes: finding multiple (short) exons is harder than finding a single (long) exon. Some facts about human genome Average of 5