基于最近邻交换树操作的基因复制与丢失算法研究的中期报告.docxVIP

基于最近邻交换树操作的基因复制与丢失算法研究的中期报告 摘要： 基因复制与丢失是自然界中常见的基因演化事件之一。通过这种演化事件，新基因的产生和旧基因的消失能够使生物通过适应环境和增加多样性来提高存活率。然而，基因复制和丢失过程的模拟与研究是困难的，因为它们涉及到大量的基因组重组。 在本文中，我们提出了一个基于最近邻交换树操作的基因复制与丢失算法，该算法可以模拟基因复制与丢失的过程，从而更好地了解生物基因组的演化方式。最近邻交换树是一个用于基因组重组和演化分析的工具，可以快速计算两个基因组之间的重组距离。在我们的算法中，我们通过模拟最近邻交换树操作来模拟基因复制和丢失的过程。 我们在现有模拟数据集上对该算法进行了实验评估，并与其他现有算法进行了比较。实验结果表明，我们的算法能够有效地模拟基因复制和丢失的过程，并能够产生与真实数据更接近的结果。 关键词：基因复制与丢失；最近邻交换树；基因组重组；演化分析。 Abstract: Gene duplication and loss are common evolutionary events in nature. Through these evolutionary events, the emergence of new genes and the disappearance of old ones can improve the survival rate of organisms by adapting to the environment and increasing diversity. However, simulating and studying the process of gene duplication and loss is difficult because it involves a large amount of genome recombination. In this paper, we propose a gene duplication and loss algorithm based on nearest-neighbor exchange tree operations, which can simulate the process of gene duplication and loss, better understanding the way of genome evolution in organisms. The nearest-neighbor exchange tree is a tool for genome recombination and evolutionary analysis, which can quickly calculate the recombination distance between two genomes. In our algorithm, we simulate the process of gene duplication and loss by simulating the nearest-neighbor exchange tree operation. We conducted experimental evaluation of the algorithm on existing simulation datasets and compared it with other existing algorithms. The experimental results show that our algorithm can effectively simulate the process of gene duplication and loss and produce results closer to real data. Keywords: Gene duplication and loss; nearest-neighbor exchange tree; genome recombination; evolutionary analysis.