新辅助化疗联合根治性宫颈切除治疗早期宫颈癌1例报道及文献复习的中期报告.docxVIP

新辅助化疗联合根治性宫颈切除治疗早期宫颈癌1例报道及文献复习的中期报告 摘要：目的 探讨新辅助化疗联合根治性宫颈切除治疗早期宫颈癌的临床疗效和安全性。方法 回顾性分析1例早期宫颈癌患者的临床资料，该患者接受新辅助化疗后行根治性宫颈切除术。结果 该患者接受1个疗程新辅助化疗后行根治性宫颈切除术。手术后肿瘤切缘阴性，术后1年随访未见瘤复发。结论 新辅助化疗联合根治性宫颈切除治疗早期宫颈癌是一种安全有效的治疗方法，但缺乏大样本的临床研究。需进一步开展大规模、长期随访的多中心前瞻性随机对照研究，以确立其在早期宫颈癌治疗中的地位。 关键词：新辅助化疗；根治性宫颈切除术；早期宫颈癌 Abstract: Objective To explore the clinical efficacy and safety of neoadjuvant chemotherapy combined with radical hysterectomy in the treatment of early cervical cancer. Methods The clinical data of one patient with early cervical cancer who underwent neoadjuvant chemotherapy and radical hysterectomy were retrospectively analyzed. Results The patient received one cycle of neoadjuvant chemotherapy before radical hysterectomy. After the surgery, the tumor margin was negative, and no tumor recurrence was observed during 1-year follow-up. Conclusion Neoadjuvant chemotherapy combined with radical hysterectomy is a safe and effective treatment for early cervical cancer. However, large-scale clinical studies are lacking, and further multicenter prospective randomized controlled trials with long-term follow-up are needed to establish its position in the treatment of early cervical cancer. Keywords: neoadjuvant chemotherapy; radical hysterectomy; early cervical cancer