低剂量CT与X线胸片对肺癌高危人群筛查的meta分析的中期报告.docx

低剂量CT与X线胸片对肺癌高危人群筛查的meta分析的中期报告 （注：以下为英文报道，其中“low-dose CT”为“低剂量CT”，“chest X-ray”为“X线胸片”） A mid-term report of a meta-analysis on the screening of lung cancer high-risk population by low-dose CT and chest X-ray has been released recently. The meta-analysis, which includes 13 randomized controlled trials with a total of 84,475 participants, aims to assess the effectiveness of low-dose CT and chest X-ray in detecting and reducing the mortality of lung cancer in high-risk individuals. The preliminary results show that low-dose CT screening reduces lung cancer mortality by 20% compared with chest X-ray screening in high-risk population. However, the overall incidence of lung cancer between the two screening methods is not significantly different. Researchers caution that the report is the mid-term result of a continuing meta-analysis and the final results may vary. They also emphasize that the findings should not be interpreted as a recommendation for universal lung cancer screening but rather used as a reference for individual clinical diagnosis and treatment. Lung cancer is a leading cause of cancer death globally and early detection is crucial for better prognosis. The high-risk population for lung cancer includes current and former heavy smokers, those who have been exposed to asbestos or other environmental carcinogens, and those with a family history of lung cancer.