感染性休克重症医学科.pptVIP

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock We randomly assigned patients who arrived at an urban emergency department with severe sepsis or septic shock to receive either six hours of early goal-directed therapy or standard therapy (as a control) before admission to the intensive care unit Rivers E, et al. N Engl J Med 2001; 345:1368–1377 本文档共64页；当前第30页；编辑于星期二\14点58分 fluid management is a matter of timing. 常规治疗：CVP≥8 ~12 mm Hg、MAP≥ 65 mm Hg EGDT: 6 h达标，ScvO2≥ 70% 结果：EGDT需大量补液(4,981±2,984 mL vs 3,4