医护人员中SARS抗体流行率.pdfVIP

ARS-CoV Immunoglobulin G in Healthcare Workers, Guangzhou, Wei-Qing Chen,* Ci-Yong Lu,* Tze-Wai Wong,†Wen-Hua Ling,* Zhong-Ning Lin,* Yuan-Tao Hao,* Qing Liu,* Ji-Qian Fang,* Yun He,* Fu-Tian Luo,* Jin Jing,* Li Ling,* Xiang Ma,* Yi-Min Liu,* Gui-Hua Chen,* Jian Huang,* Yuan-Sen Jiang,* Wen-Qi Jiang,* He-Qun Zou,* and Guang-Mei Yan* To determine the prevalence of inapparent infection 2003, a total of 1,284 probable SARS cases had been with severe acute respiratory syndrome (SARS) among reported in Guangzhou (3). healthcare workers, we performed a serosurvey to test for In most cases, the disease was spread through close immunoglobulin (Ig) G antibodies to the SARS contact with an infected (4). A high idence of (SARS-CoV) among 1,147 healthcare workers in 3 hospi- SARS was observed among healthcare workers, especial- tals that admitted SARS patients in mid-May 2003. Among them were 90 healthcare workers with SARS. As a refer- ly during the early stages of the SARS epidemic (5–8); ence group, 709 healthcare workers who worked in 2 hos- healthcare workers were likely exposured to the SARS pitals that never admitted any SARS patients were similarly (SARS-CoV) at the work ce. Also, SARS- tested. The seroprevalence rate was 88.9% (80/90) for CoV can survive for many hours on environmental sur- healthcare workers with SARS and 1.4% (15/1,057) for faces (5); therefore, infection through contact with healthcare workers who were apparently healthy. The sero- contaminated fomites is