妊娠期皮肤病课件.pptxVIP

妊娠期皮肤病 Hyperpigmentation 色素沉着 • Increased melanocyte-stimulating hormone • Accentuation on areolae, genital skin, and linea alba • Usually regresses postpartum • Occurs in 90% of pregnant women Melasma 黄褐斑 • Occurs in 70% of pregnant women • Also seen with oral contraceptivetherapy • Centrofacial, malar, and mandibular patterns • Excessive melanin in epidermis or dermal macrophages • Worsens with UVB exposure Hirsutism 多毛症 • Face, limbs, and back • Regresses within 6 months postpartum • Slowed conversion from anagen to telogen hairs • Transverse grooving • Brittleness • Distal onycholysis Nail changes 甲改变 内分泌腺活性增加 Increased eccrine gland activity • Miliaria • Dyshidrotic eczema • Hyperhidrosis Decreased apocrine gland activity • Hidradenitis suppurativa alleviated 大汗腺活动性减少 腺活动性增加 • Exacerbation of acne vulgaris • Montgomery’s tubercles enlarge Increased sebaceous gland activity 皮脂 Striae distensae妊振纹 • Occur in 90% of pregnant women • Pink or purple atrophic longitudinal bands • Caused by increased adrenocortical activity • Fade postpartum to persistent pale atrophic bands • Spider nevi • Palmar erythema • Nonpitting facial edema • Venous varicosities: Legs • Vasomotor instability • Dermographism Vascular changes血管变化 • Edema and hyperemia of gingivae Dermatoses exacerbated by pregnancy 妊振期加重的皮肤病 Atopic eczema 特应性皮炎 • May deteriorate or remit during pregnancy • limbs and/or trunk and face • Irritant hand dermatitis and nipple eczema common postpartum • Treatment: topical corticosteroids, emollients, UVB • May present for the first time in pregnancy in predisposed person • Most common type : chronic plaque psoriasis • Differential diagnosis of pustular variant from impetigo herpetiformis may be difficult • Topical treatment: Dithranol, calcipotriol, tar, a