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Microfilament
Centriole
Nucleus
Ribosomes
Mitochondrion
Rough
endoplasmic
reticulum
Golgiapparatus
Amammaliancell
Plasmamembrane
Lysosome
Smooth
endoplasmicreticulum
Microvillus
·Thenucleusisamembrane
boundstructurethatcontainsthecellshereditaryinformationandcontrolsthecellsgrowthand
reproduction.
·Itiscommonlythemost
prominentorganelleinthecell
Nucleus
·Thenuclearcontentislocatedinthenuclearlumenandissurroundedbya
doublemembraneornuclearenvelope,
composedofinnermembraneandoutermembrane.
·Theoutermembraneiscontiguouswith
theER
·Thenuclearmembranecontainsnuclearpores,whichprovideselectiveaccessintoandoutofthenuclearlumen
·Theinnermembranehasaproteinlining
calledthenuclearlamina,whichbindsto
chromatinandothernuclearcomponents.
NuclearMembranes
-nuclearporecomplexislarge-about120millionDaltons
-30differentproteinsfoundinpore;
basicsubunitrepeated16times.“Centralgranulenowcalledtransporter
functionstomovemoleculesthroughpore.Thereisaringofproteinsthatanchors
poretoN.E.andthebasketoffiberswithunknownfunction
-noobviousmotorproteinswerefound
TheNuclearPoreComplexes
continuousaqueouschannelbetweencytoplasmnucleoplasm
(C)
61pm
1CARANDPUBLSEC
·StretchofDNAwithrRNAgenes
nucleolarorganizingregion=(NOR)
·Ribosomalproteinsaresynthesizedincytoplasmandtransportedintothenucleus
·TheseproteinsselfassociatewithappropriaterRNAduringrRNA
synthesisformingimmature
ribosomalsubunits
·Ribosomesfinishselfassemblyincytoplasm
TheNucleolus
·TheregionofthenucleuswhereportionsofchromosomesthatcontaingenescodingforribosomalRNAaretranscribedandribosomalsubunitsare
assembled
/library/weekly/aa032300a.htm
EndoplasmicReticulum
激光共聚焦显微镜下的ER
KEDLR-GFP
·ERisahomeforvariousenzymesinvolvedinproteinfolding,drugdetoxification,membrane
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