核素显像对原发性甲状旁腺功能亢进可视化诊断进展.pdfVIP

·88·doi10.12122/j.issn.1674-4500.2024.01.16分子影像学杂志,2024,47(1):88-92

核素显像对原发性甲状旁腺功能亢进可视化诊断进展核素显像对原发性甲状旁腺功能亢进可视化诊断进展

121

邬心爱，邬永军，王雪梅

12

内蒙古医科大学附属医院核医学科，内蒙古自治区分子影像学重点实验室，内蒙古呼和浩特010000；鄂尔

多斯东胜区人民医院急诊科，内蒙古鄂尔多斯017000

摘要：原发性甲状旁腺功能亢进（PHPT）是一种常见的内分泌疾病，常伴有钙、磷代谢紊乱及多系统病变。手术切除是治疗

99m

PHPT的主要手段，随着微创手术的推广应用，术前分子影像学精准定位成为迫切需要。核素显像双时相Tc-MIBISPECT/

111899m1118

CT、C-choline及F-FluorocholinePET/CT一直是PHPT术前定位研究的热点，现就Tc-MIBI、C-choline及F-Fluorocholine

基本显像原理，三种核素显像方式在异位/复发病变、多腺体病变、PTH升高与核素显像结果不一致及既往颈部手术史的PHPT

术前定位临床应用优缺点新进展相关文献进行综述。

关键词：原发性甲状旁腺功能亢进；SPECT/CT；PET/CT；术前定位

Progressinvisualizationdiagnosisofprimaryhyperparathyroidismusingnuclide

imaging

121

WUXinai,WUYongjun,WANGXuemei

1DepartmentofNuclearMedicine,AffiliatedHospitalofInnerMongoliaMedicalUniversity,KeyLaboratoryofMolecularImagingofInner

MongoliaAutonomousRegion,Hohhot010000,China;2DepartmentofEmergency,OrdosDongshengDistrictPeoplesHospital,Ordos

017000,China

Abstract:Primaryhyperparathyroidism(PHPT)isacommonendocrinedisease,oftenaccompaniedbycalciumand

phosphorusmetabolismdisordersandmulti-systemlesions.SurgicalresectionisthemainmethodforthetreatmentofPHPT.

Withthepopularizationandapplicationofminimallyinvasivesurgery,preoperativemolecularimaginghasbecomeanurgent

needforaccuratelocalization.Radionuclideimagingofdual-phase99mTc-MIBISPECT/CT,11C-cholineand18F-