Granisetron-Hydrochloride-Standard-BRL-43694A-Standard-DataSheet-生命科学试剂-MCE.pdf

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

GranisetronHydrochloride(Standard)

Cat.No.:HY-B0071AR

CASNo.:107007-99-8

Synonyms:BRL43694A(Standard)

分⼦式:C₁₈H₂₅ClN₄O

分⼦量:348.87

作⽤靶点:5-HTReceptor

作⽤通路:GPCR/GProtein;NeuronalSignaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

溶解性数据

体外实验H2O:100mg/mL(286.64mM;Needultrasonic)

DMSO:7.69mg/mL(22.04mM;Needultrasonic)

Mass

Solvent

1mg5mg10mg

Concentration

制备储备液1mM2.8664mL14.3320mL28.6640mL

5mM0.5733mL2.8664mL5.7328mL

10mM0.2866mL1.4332mL2.8664mL

BIOLOGICALACTIVITY

⽣物活性Granisetron(Hydrochloride)(Standard)是Granisetron(Hydrochloride)的分析标准品。本产品⽤于研究及分

析应⽤。Granisetron(BRL43694A)盐酸盐是5-HT3受体拮抗剂，可作为化疗后⽌吐剂。

IC50TargetIC50:17uM(5-HT3receptor)[1].

REFERENCES

[1].SangerGJ,Nels