Flutamide-Standard-SCH-13521-Standard-DataSheet-生命科学试剂-MCE.pdf

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Flutamide(Standard)

Cat.No.:HY-B0022R

CASNo.:13311-84-7

Synonyms:SCH13521(Standard)

分⼦式:C₁₁H₁₁F₃N₂O₃

分⼦量:276.21

作⽤靶点:AndrogenReceptor

作⽤通路:VitaminDRelated/NuclearReceptor

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

溶解性数据

体外实验DMSO:100mg/mL(362.04mM;Needultrasonic)

H2O:0.1mg/mL(insoluble)

Mass

Solvent

1mg5mg10mg

Concentration

制备储备液1mM3.6204mL18.1022mL36.2043mL

5mM0.7241mL3.6204mL7.2409mL

10mM0.3620mL1.8102mL3.6204mL

BIOLOGICALACTIVITY

⽣物活性Flutamide(Standard)是Flutamide的分析标准品。本产品⽤于研究及分析应⽤。Flutamide是雄激素受体(

AndrogenReceptor)拮抗剂，Ki=55nM。Flutamide可抑制前列腺癌发展，并与Docetaxel(HY-B0011)具有

协同增效作⽤。Flutamide还有潜⼒防⽌⾼温引起的多器官功能障碍综合征。

REFERENCES

[1].SimardJ,etal.C