MCTR3-DataSheet-生命科学试剂-MCE.pdf

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Inhibitors•ScreeningLibraries•Proteins

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MCTR3

Cat.No.:HY-125516

CASNo.:1784701-63-8

分⼦式:C₂₅H₃₇NO₅S

分⼦量:463.63

作⽤靶点:Others

作⽤通路:Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性MCTR3是⼀种促溶解的maresin偶联物，可以减少炎症反应并且促进组织再⽣。MCTR3可以改善LPS诱导的

急性肺损伤和关节炎[1][2][3]。

体外研究MCTR3(1nM)alleviatesLPS-inducedcellulardamageandoxidativestress,reducesapoptosisand

autophagy-relatedproteinproductionincellsMLE12throughtheALX/PINK1pathway[1].

MCTR3(1nM)enhancesefferocytosisandbacterialphagocytosisbyexudateleukocytes,reducesneutrophil

infiltrationandeicosanoids[2].

Immunofluorescence[1]

CellLine:MLE12

Concentration:1nM

IncubationTime:24h

Result:DecreasedLPS-stimulatedexpressionsofPINK1andParkin.

WesternBlotAnalysis[1]

CellLine:MLE12

Concentration:1nM

IncubationTime:24h

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