《病理学》肿瘤-英文教学课件（非AI生成）.pptx

Neoplasm/Tumor肿瘤(1)1

Malignanttumors!1981-2015Pancreaticneuroendocrinetumor胰腺神经内分泌肿瘤Breastcancer乳腺癌2

GlobalCancerStatistics

56%64%indevelopingcountries3

CancerStatisticsinUS,2014CACANCERJCLIN2014;64(1):9-29

新发病例（1,665,540）4

CACANCERJCLIN2014;64(1):9-29

CancerStatisticsinUS,2014死亡病例（585,720）5

Trendsincancerincidenceanddeathratesbysex,unitedstates,1975-2010CACANCERJCLIN2014;64(1):9-296

SixpersonareDxofCancerinoneminuteMorbidity(发病率)Estimatednewcases3,120,000Mortality(死亡率)Estimateddeaths2,700,000LungStomachColorectumLiverBreastEsophagusCervixProstateOvaryuterusTop10CancersinChinesecitiesmorbiditymortalityCancerStatisticsinChina,2012No.1causeofhumandeathinChina7

Lungcancer肺癌8

Hepatocellularcarcinoma肝细胞癌9

Colorectalcancer结直肠癌10

Esophagealcancer食管癌11

stomachCancer?Ulcer?12

Inflammation?Cancer?Pathologicdiagnosis!13

PleaserememberPathologicevaluationisstillthegoldstandardintumordiagnosisTumorpathologyisthestartingpointforunderstandingoftumor14

Definition**Characteristicsofneoplasm**（特征）Clinicalfeaturesofneoplasm（临床特征）Diagnosisoftumor*Themolecularbasisofcancer（分子发病途径）EtiologyofcancerCommontumors*Outlines15

DefinitionAneoplasmisanabnormalmassoftissue,thegrowthofwhichexceedsandisuncoordinatedwiththatofthenormaltissuesandpersistthesameexcessivemanneraftercessationofthestimuliwhichevokethechange肿瘤是机体在各种致瘤因素(oncogenicfactor)的作用下，局部组织的细胞在基因水平上失掉了对其生长的正常调控，导致异常增生而形成的新生物(neoplasm)，通常形成肿块(mass)原因过程结果16

GlossaryNeoplasia(newgrowthinGreek,肿瘤形成)含良Theprocessofabnormalanduncontrolledgrowthofcellsinatissueororgan,usuallyformingadistinctmassTumor(肿瘤):swellinginLatin,?asynonymofneoplasm（更加普通，泛指）含良Cancer:malignantneoplasm(恶性肿瘤),carcinos?orcrabinGreek)（即：癌症）17

GlossaryOncology(肿瘤学):thestudyofneoplasmsonco（癌）Carcinogenesis(Tumorigen