Amyloid-β-Protein-3-42-TFA-生命科学试剂-MCE.pdf

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Amyloidβ-Protein(3-42)TFA

Cat.No.:HY-P4886A

分⼦式:C₁₉₆H₃₀₁N₅₃O₅₆S.xC₂HF₃O₂

Sequence:Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Le

u-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Il

e-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala

SequenceShortening:EFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

作⽤靶点:Amyloid-β

作⽤通路:NeuronalSignaling

储存⽅式:Sealedstorage,awayfrommoisture

Powder-80°C2years

-20°C1year

Insolvent-80°C6months

-20°C1month

溶解性数据

体外实验H2O:25mg/mL(Needultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造

成的产品失效。储备液的保存⽅式和期限：-80°C,6months;-20°C,1month(sealedstorage,awayfrom

moisture)。-80°C储存时，请在6个⽉内使⽤，-20°C储存时，请在1个⽉内使⽤。

BIOLOGICALACTIVITY

⽣物活性Amyloidβ-Protein(3-42)TFA是Pyr肽的前体。焦⾕氨酸修饰的Aβ(pEAβ)(3-42)是阿兹海默症淀粉样板

块的核⼼。pEAβ(3-42)加速Aβ(1-42)的聚集，⽽Aβ(1-42)显著减慢pEAβ(3-42)的初级和次级成核。

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