Chavicol-p-Hydroxyallylbenzene-生命科学试剂-MCE.pdf

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

Chavicol

Cat.No.:HY-W159754

CASNo.:501-92-8

Synonyms:p-Hydroxyallylbenzene

分⼦式:C₉H₁₀O

分⼦量:134.18

作⽤靶点:Cholinesterase(ChE)

作⽤通路:NeuronalSignaling

储存⽅式:4°C,storedundernitrogen

*Insolvent:-80°C,6months;-20°C,1month(storedunder

nitrogen)

BIOLOGICALACTIVITY

⽣物活性Chavicol(p-Hydroxyallylbenzene,compound6)可抑制⼄酰胆碱酯酶(Cholinesterase(ChE))，IC50为7.42

μM。Chavicol具有抗癌活性，可抑制癌细胞的⽣长、存活、迁移和侵袭，在A-549细胞中，细胞毒作⽤显著

，约为31μg/mL[1][2]。

REFERENCES

[1].HaixiaoLu,etal.TzuminAandB,twonewlignanderivativesfromthebarksofSassafrastzumu.NatProdRes.2017Apr;31(7):829-

834.

[2].ChellasamyPanneerselvam,etal.AnticanceractivityofbioactivecompoundchavicolaspotentialtoxicagainsthumanlungcancerA549

cells.JournalofDrugDeliveryScienceandTechnology.Volume73,July2022,103442.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearch