C16G2-生命科学试剂-MCE.pdf

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C16G2

Cat.No.:HY-P10696

CASNo.:2154327-48-5

分⼦式:C₁₉₀H₃₁₀N₅₈O₄₂

分⼦量:4078.93

Sequence:Thr-Phe-Phe-Arg-Leu-Phe-Asn-Arg-Ser-Phe-Thr-Gln-Ala-Leu-

Gly-Lys-Gly-Gly-Gly-Lys-Asn-Leu-Arg-Ile-Ile-Arg-Lys-Gly-Ile-Hi

s-Ile-Ile-Lys-Lys-Tyr-NH2

SequenceShortening:TFFRLFNRSFTQALGKGGGKNLRIIRKGIHIIKKY-NH2

作⽤靶点:Bacterial;Antibiotic

作⽤通路:Anti-infection

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性C16G2是⼀种特异性靶向抗菌肽(STAMP)，靶向致龋⼝腔病原菌Streptococcusmutans。C16G2通过特异性

识别并破坏细菌的细胞膜，导致⼩分⼦泄漏和膜电位丧失，从⽽实现细菌的杀灭。与⼴谱抗菌肽不同，C16G2

对Streptococcusmutans具有更⾼的选择性和效能[1]。

REFERENCES

[1].KaplanCW,etal.Selectivemembranedisruption:modeofactionofC16G2,aspecificallytargetedantimicrobialpeptide.Antimicrob

AgentsChemother.2011Jul;55(7):3446-52.

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