CPP9-TFA-生命科学试剂-MCE.pdf

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CPP9TFA

Cat.No.:HY-P10644A

分⼦式:C₅₉H₈₀F₁₂N₂₀O₁₆

分⼦量:1553.37

Sequence:Cyclo({d-Phe}-{2-Nal}-Arg-{d-Arg}-Arg-{d-Arg}-Gln)

SequenceShortening:Cyclo({d-Phe}-{2-Nal}-R-{d-Arg}-R-{d-Arg}-Q)

作⽤靶点:Others

作⽤通路:Others

储存⽅式:Sealedstorage,awayfrommoisture

Powder-80°C2years

-20°C1year

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性CPP9TFA是⼀种⼩型、两亲性、环状细胞穿透肽(CPP)。CPP直接与质膜磷脂结合，通过内吞作⽤进⼊哺乳动

物细胞，然后从内体有效释放。CPP9TFA可⽤于药物和化学探针的细胞内递送。

REFERENCES

[1].QianZ,etal.DiscoveryandMechanismofHighlyEfficientCyclicCell-PenetratingPeptides.Biochemistry.2016May10;55(18):2601-12.

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