Peimine-Standard-生命科学试剂-MCE.pdf

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Peimine(Standard)

Cat.No.:HY-N0212R

CASNo.:23496-41-5

分⼦式:C₂₇H₄₅NO₃

分⼦量:431.65

作⽤靶点:Apoptosis;Apoptosis;InterleukinRelated;InterleukinRelated;

TNFReceptor;TNFReceptor;p38MAPK;p38MAPK;NF-κB;

NF-κB

作⽤通路:Apoptosis;Immunology/Inflammation;MAPK/ERKPathway;

NF-κB

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Peimine(Standard)是Peimine的分析标准品。本产品⽤于研究及分析应⽤。Peimine(Verticine;

Dihydroisoimperialine)是⼀种具有⼝服活性的天然产物。Peimine具有消炎、镇痛、⽌咳的作⽤。Peimine

可⽤于癌症和炎症相关研究[1][2][3][4][5][6][7]。

REFERENCES

[1].YiPF,etal.Peimineimpairspro-inflammatorycytokinesecretionthroughtheinhibitionoftheactivationofNF-κBandMAPKinLPS-

inducedRAW264.7macrophages.ImmunopharmacolImmunotoxicol.2013Oct;35(5):567-72.

[2].ChenK,LvZT,ZhouCH,etal.Peiminesuppressesinterleukin‑1β‑inducedinflammationviaMAPKdownregulationinchondrocytes.Int

JMolMed.2019;43(5):2241-2251.

[3].TanH,etal.Peimineinhibitsthegrowthandmotilityofprostatecancercellsandinducesapoptosisbydisruptionofintracellularcalcium

homeostasisthroughCa2+/CaMKII/JNKpathway.JCellBiochem.2020Jan;121(1):81-