Probenecid-sodium-生命科学试剂-MCE.pdf

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Inhibitors•ScreeningLibraries•Proteins

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Probenecidsodium

Cat.No.:HY-W404916

CASNo.:23795-03-1

分⼦式:C₁₃H₁₈NNaO₄S

分⼦量:307.34

作⽤靶点:TRPChannel;Bacterial;HIV

作⽤通路:MembraneTransporter/IonChannel;NeuronalSignaling;Anti-

infection

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Probenecidsodium是丙磺舒的钠盐。Probenecid是⼀种有效的选择性瞬时受体电位⾹草酸受体通道2(

TRPV2)激动剂。Probenecid还抑制pannexin1通道。

客户使⽤本产品发表的科研⽂献

•CellRes.2022Apr22.

•Immunity.2022Mar15;S1074-7613(22)00124-8.

•CellMolImmunol.2020Mar;17(3):261-271.

•IntJBiolSci.2022Apr11;18(7):2914-2931.

•TranslRes.2024May9:271:26-39.

Seemorecustomervalidationsonwww.MedChemE

REFERENCES

[1].KochSE,etal.Probenecid:noveluseasanon-injuriouspositiveinotropeactingviacardiacTRPV2stimulation.JMolCellCardiol.2012

Jul;53(1):134-44.

[2].BakosE,etal.InteractionsofthehumanmultidrugresistanceproteinsMRP1andMRP2withorganicanions.MolPharmacol.2000

Apr;57(4):760-8.

[3].GreeneTA,etal.ProbenecidinhibitsthehumanbittertastereceptorTAS2R16andsuppressesbitterperceptionofsalicin.PLoSOne.

2011;6(5):e20123.

1/2MasterofBioactiveMolecules—