N-S-Bis-Fmoc-Glutathione-TFA-生命科学试剂-MCE.pdf

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Inhibitors•ScreeningLibraries•Proteins

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N,S-Bis-Fmoc-GlutathioneTFA

Cat.No.:HY-P4277A

分⼦式:C₄₂H₃₈F₃N₃O₁₂S

分⼦量:865.82

Sequence:{Fmoc}-{γ-Glu(({Cys-Fmoc})-Gly)}

SequenceShortening:{Fmoc}-{γ-Glu(({Cys-Fmoc})-Gly)}

作⽤靶点:Glyoxalase(GLO)

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Sealedstorage,awayfrommoisture

Powder-80°C2years

-20°C1year

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性N,S-Bis-Fmoc-GlutathioneTFA是⼀种有效的glyoxalaseII抑制剂，Ki值为0.75μM，IC50值为2.5μM

[1]。

REFERENCES

[1].NortonSJ,etal.InhibitorsandinhibitionstudiesofmammalianglyoxalaseIIactivity.BiochemSocTrans.1993May;21(2):545-9.

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