MATLAB在医学中的应用课件.ppt

MATLAB在医学中的应用MATLAB在医学中的应用

MATLAB在医学中的应用内容：1)介绍机能核磁共振成像技术（fMRI:functionalMagneticResonanceImaging)２)介绍MATLAB上开发的fMRI分析软件SPM(StatisticalParametricMapping)

MATLAB在医学中的应用机能核磁共振成像fMRI

MATLAB在医学中的应用fMRISetup–whatitreallylookslike!

MATLAB在医学中的应用MagnetSafetyThewhoppingstrengthofthemagnetmakessafetyessential.Thingsfly–Evenbigthings!ScreensubjectscarefullyWereyoueverasoldier?Makesureyouandallyourstudentsstaffareawareofhazzards!Developstrategiesforscreeningyourselfeverytimeyouenterthemagnet!

MATLAB在医学中的应用fMRISetup

MATLAB在医学中的应用fMRIExperimentStages:Prep1)PreparesubjectConsentformSafetyscreeningInstructions2)Shimmingputtingbodyinmagneticfieldmakesitnon-uniformadjust3orthogonalweakmagnetstomakemagneticfieldashomogenousaspossible3)Sagittals Takeimagesalongthemidlinetousetoplanslices

MATLAB在医学中的应用fMRIExperimentStages:Anatomical4)Takeanatomical(T1)imageshigh-resolutionimages(e.g.,1x1x2.5mm)3Ddata:3spatialdimensions,sampledatonepointintime64anatomicalslicestakes~5minutes

MATLAB在医学中的应用SliceThicknesse.g.,6mmNumberofSlicese.g.,10SAGITTALSLICEIN-PLANESLICEFieldofView(FOV)e.g.,19.2cmVOXEL(VolumetricPixel)3mm3mm6mmSliceTerminologyMatrixSizee.g.,64x64In-planeresolutione.g.,192mm/64=3mm

MATLAB在医学中的应用fMRIExperimentStages:Functional5)Takefunctional(T2*)imagesimagesareindirectlyrelatedtoneuralactivityusuallylowresolutionimages(3x3x5mm)allslicesatonetime=avolume(sometimesalsocalledanimage)samplemanyvolumes(timepoints)(e.g.,1volumeevery2secondsfor150volumes=300sec=5minutes)4Ddata:3spatial,1temporalfirstvolume(2sectoacquire)…

MATLAB在医学中的应用StatisticalMapsuperimposedonanatomicalMRIimage~2sFunctionalimagesTimeCondition1Condition2...~5minTimefMRISignal(%change)ROITimeCourseConditionActivationStatisticsRegionofinterest(ROI)

MATLAB在医学中的应用fMRIPhysics

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