Pyridoxal-5-phosphate-monohydrate-Standard-生命科学试剂-MCE.pdf

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Pyridoxal5-phosphate(monohydrate)(Standard)

Cat.No.:HY-W011727AR

CASNo.:41468-25-1

分⼦式:C₈H₁₂NO₇P

分⼦量:265.16

作⽤靶点:EndogenousMetabolite;Amyloid-β;ERK

作⽤通路:MetabolicEnzyme/Protease;NeuronalSignaling;MAPK/ERK

Pathway;StemCell/Wnt

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Pyridoxal5-phosphate(monohydrate)(Standard)是Pyridoxal5-phosphate(monohydrate)的分析标准品

。本产品⽤于研究及分析应⽤。Pyridoxal5-phosphatehydrate是维⽣素B6的活性形式，它是多种酶(包括

可催化神经递质多巴胺和5-羟⾊胺⽣产的最后阶段的芳族L-氨基酸脱羧酶)的重要辅因⼦。Pyridoxal5-

phosphatehydrate是维⽣素B6在细胞

IC50TargetIC50:activeformofvitaminB6[1]

REFERENCES

[1].AllenGF,etal.Pyridoxal5-phosphatedeficiencycausesalossofaromaticL-aminoaciddecarboxylaseinpatientsandhuman

neuroblastomacells,implicationsforaromaticL-aminoaciddecarboxylaseandvitaminB(6)deficiencystates.JNeurochem.2010

Jul;114(1):87-96.

[2].Calderón-OspinaCA,etal.BVitaminsinthenervoussystem:Currentknowledgeofthebiochemicalmodesofactionandsynergiesof

thiamine,pyridoxine,andcobalamin.CNSNeurosciTher.2020Jan;26(1):5-13.

[3].ZhangP,etal.,HighconcentrationsofpyridoxalstimulatetheexpressionofIGFBP1inHepG2