大环内酯类抗生素联合甲泼尼龙治疗儿童肺炎支原体肺炎的临床疗效分析.docx

大环内酯类抗生素联合甲泼尼龙治疗儿童肺炎支原体肺炎的临床疗效分析\o分享到微博\o分享到微信\o分享到QQ\o分享到QQ空间

【摘要】目的：评价和分析大环内酯类抗生素联合甲泼尼龙治疗儿童肺炎支原体肺炎的效果。方法：研究时间为2021年1月—2023年9月，研究对象为66例肺炎支原体肺炎患儿，对照组患儿单用大环内酯类抗生素治疗，观察组在对照组基础上加用甲泼尼龙治疗，比较两组疗效。结果：观察组患儿治疗总有效率明显高于对照组，优势显著（P0.05）；观察组患儿不良反应发生率明显低于对照组，有明显差异性（P0.05）；观察组患儿临床症状消退时间比对照组更短，优势明显（P0.05）；治疗后，观察组患儿的生活质量评分比对照组更高，差异有统计学意义（P0.05）。结论：大环内酯类抗生素联合甲泼尼龙治疗儿童肺炎支原体肺炎的效果显著，可以减少不良反应，能够促使症状尽快消退，有利于提升康复效果，预后更理想，具有较好的临床推广性。

【关键词】儿童肺炎支原体肺炎；大环内酯类抗生素；甲泼尼龙；治疗效果

Clinicaleffectanalysisofmacrolideantibioticscombinedwithmethylprednisoloneinthetreatmentofmycoplasmapneumoniaepneumoniainchildren

ZHOUZhuping

DepartmentofPediatrics，XuanchengPeople’sHospital，Xuancheng，Anhui242000，China

【Abstract】Objective：Toevaluateandanalyzetheefficacyofmacrolideantibioticscombinedwithmethylprednisoloneinthetreatmentofmycoplasmapneumoniaepneumoniainchildren.Methods：ThestudyperiodwasfromJanuary2021toSeptember2023，andthestudyobjectswere66childrenwithmycoplasmapneumoniaepneumonia.Thecontrolgroupwastreatedwithmacrolideantibioticsalone，andtheobservationgroupwastreatedwithmethylprednisoloneonthebasisofthecontrolgroup.Thetherapeuticeffectsofthetwogroupswerecompared.Results：Thetotaleffectiverateoftreatmentintheobservationgroupwassignificantlyhigherthanthatinthecontrolgroup（P0.05）；Theincidenceofadversereactionsintheobservationgroupwassignificantlylowerthanthatinthecontrolgroup（P0.05）；Theclinicalsymptomsresolutiontimeintheobservationgroupwasshorterthanthatinthecontrolgroup（P0.05）；Aftertreatment，thequalityoflifescoreoftheobservationgroupwashigherthanthatofthecontrolgroup，andthedifferencewasstatisticallysignificant（P0.05）.Conclusion：Thecombinationofmacrolideantibioticsandmethylprednisolonehassignificanttherapeuticeffect，whichcanreduceadversereactions，promotethesymptomstosubsideassoonaspossible，andisconducivetoimp