Maropitant-citrate-生命科学试剂-MCE.pdfVIP

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Maropitantcitrate

Cat.No.:HY-10053B

CASNo.:862543-54-2

分⼦式:C₃₈H₄₈N₂O₈

分⼦量:660.8

作⽤靶点:NeurokininReceptor

作⽤通路:GPCR/GProtein;NeuronalSignaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Maropitantcitrate是⼀种⼝服的NK1受体拮抗剂。Maropitantcitrate可防⽌呕吐并抑制溃疡性⽪炎[1][2]。

IC50TargetNK1

REFERENCES

[1].HayKrausBL.Efficacyoforallyadministeredmaropitantcitrateinpreventingvomitingassociatedwithhydromorphoneadministrationin

dogs.JAmVetMedAssoc.2014May15;244(10):1164-9.

[2].Williams-FritzeMJ,etal.MaropitantcitratefortreatmentofulcerativedermatitisinmicewithaC57BL/6background.JAmAssocLab

AnimSci.2011Mar;50(2):221-6.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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