N-Acetyl-D-glucosamine-d3-N-Acetyl-2-amino-2-deoxy-D-glucose-d-sub-3-sub-生命科学试剂-MCE.pdfVIP

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N-Acetyl-D-glucosamine-d3

Cat.No.:HY-A0132S14

CASNo.:77369-11-0

Synonyms:N-Acetyl-2-amino-2-deoxy-D-glucose-d3

分⼦式:C₈H₁₂D₃NO₆

分⼦量:224.23

作⽤靶点:Isotope-LabeledCompounds;EndogenousMetabolite;Drug

Derivative;InterleukinRelated;DrugIsomer

作⽤通路:Others;MetabolicEnzyme/Protease;

Immunology/Inflammation

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性N-Acetyl-D-glucosamine-d3(N-Acetyl-2-amino-2-deoxy-D-glucose-d3)是氘代标记的N-Acetyl-D-

glucosamine.N-Acetyl-D-Glucosamine(N-Acetyl-2-amino-2-deoxy-D-glucose)是N-⼄酰基葡萄糖胺的D异

构体，是⼀种具有⼝服活性的葡萄糖单糖衍⽣物，具有抗肿瘤和抗炎特性。N-Acetyl-D-Glucosamine也是细

菌的代谢物，发现于Escherichiacoli。N-Acetyl-D-Glucosamine可诱导Candidaalbicans中酵母-菌丝转化。

N-Acetyl-D-Glucosamine还能促进兔软⾻损伤的愈合[1][2][3]。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal