Tryptophol-d4-Indole-3-ethanol-d-sub-4-sub-生命科学试剂-MCE.pdfVIP

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

Tryptophol-d4

Cat.No.:HY-W750342

CASNo.:75238-45-8

Synonyms:Indole-3-ethanol-d

4

分⼦式:C₁₀H₇D₄NO

分⼦量:165.23

作⽤靶点:Isotope-LabeledCompounds;EndogenousMetabolite;

Apoptosis;Caspase;Bacterial

作⽤通路:Others;MetabolicEnzyme/Protease;Apoptosis;Anti-infection

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Tryptophol-d4(Indole-3-ethanol-d4)是氘标记的Tryptophol(HY-W010155)。Tryptophol是⼀种芳⾹醇和微

⽣物产⽣的次级代谢产物。Tryptophol诱导凋亡(apoptosis)和caspase-8切割。Tryptophol抑制

Cunninghamellablakesleeana⽣物膜。Tryptophol具有抗噬菌体感染、调节⽣物膜形成、抗炎、溶⾎、诱导

睡眠、改变体温、影响惊厥易感性以及调节免疫等活性。Tryptophol⽤于⾮洲锥⾍病、睡眠障碍、癫痫等疾病

的相关研究。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention